Caffeine sensitivity is a hallmark of Explorers because they are almost always what geneticists call 'Slow Acetylators'-- a fancy way of saying drugs spend a long time in their livers, going round and round, when they should just get processed and eliminated. Like a man who shakes his fist at the bicycle in the road that just missed hitting him -and totally ignores the bus heading his way, the liver of the Explorer GenoType will often overreact to small levels of toxins, to the point that it lets larger amounts of toxins pass by without doing anything about them.
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