Keloid steroid injection results

Keloids are an important medical problem which are often under appreciated by the medical community. Dr. Michael Tirgan has spent many years evaluating and treating patients with keloids on different regions of the body. The Atlas of Ear Keloids presents new insights into the natural history of keloids and provides a perspective that many of the standard surgical approaches may actually lead to progression of these tumors on ear. He presents good examples of an alternative treatment with cryotherapy that has convincingly eliminated some of the most troublesome keloids on ear. This book will provide valuable information to patients with keloids on ear and to medical professionals that treat these lesions.

For severe cases, the keloid can surgically excised and given x-ray treatments to the site immediately afterwards, usually the on the same day. This works in about 85% of the most severe cases. Electron beam radiation can be used, which will not go deep enough to affect internal organs. Orthovoltage radiation is more penetrating and slightly more effective. There have not been any reports of this causing any form of cancer in many years of use, but it is very expensive. Silicone pads and creams are sold over the counter for use on keloids. These do benefit hypertrophic scars but will not cure a true keloid. However, they can reduce pain, swelling and itching from a keloid. They usually take 3 months or more to work.

Meshkinpour et al (2005) examined the safety and effectiveness of the ThermaCool TC radiofrequency system for treatment of hypertrophic and keloid scars and assessed treatment associated collagen changes.  Six subjects with hypertrophic and 4 with keloid scars were treated with the ThermaCool device: 1/3 of the scar received no treatment (control), 1/3 received one treatment and 1/3 received 2 treatments (4-week interval).  Scars were graded before and then 12 and 24 weeks after treatment on symptoms, pigmentation, vascularity, pliability, and height.  Biopsies were taken from 4 subjects with hypertrophic scars and evaluated with hematoxylin and eosin (H & E) staining, multi-photon microscopy, and pro-collagen I and III immunohistochemistry.  No adverse treatment effects occurred.  Clinical and H & E evaluation revealed no significant differences between control and treatment sites.  Differences in collagen morphology were detected in some subjects.  Increased collagen production (type III > type I) was observed, appeared to peak between 6 and 10 weeks post-treatment and had not returned to baseline even after 12 weeks.  The authors concluded that use of the thermage radiofrequency device on hypertrophic scars resulted in collagen fibril morphology and production changes.  ThermaCool alone did not achieve clinical hypertrophic scar or keloid improvement.  They noted that the collagen effects of this device should be studied further to optimize its therapeutic potential for all indications.

Keloids were described by Egyptian surgeons around 1700 BCE, recorded in the Smith papyrus, regarding surgical techniques. [ citation needed ] Baron Jean-Louis Alibert (1768–1837) identified the keloid as an entity in 1806. [ citation needed ] He called them cancroïde , later changing the name to chéloïde to avoid confusion with cancer. The word is derived from the Greek χηλή , chele , meaning " hoof ", here in the sense of "crab pincers ", and the suffix -oid , meaning "like".

Keloid steroid injection results

keloid steroid injection results

Keloids were described by Egyptian surgeons around 1700 BCE, recorded in the Smith papyrus, regarding surgical techniques. [ citation needed ] Baron Jean-Louis Alibert (1768–1837) identified the keloid as an entity in 1806. [ citation needed ] He called them cancroïde , later changing the name to chéloïde to avoid confusion with cancer. The word is derived from the Greek χηλή , chele , meaning " hoof ", here in the sense of "crab pincers ", and the suffix -oid , meaning "like".

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